Integrative multiomic profiling of triple-negative breast cancer for identifying suitable therapies
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In mammalian nervous systems, many different types of chemical substances, including amino acids (e.g., glutamate), monoamines (e.g., dopamine, norepinephrine), acetylcholine, peptides (e.g., substance P), serve as neurotransmitters to bind their corresponding receptors, then activate ion channels, and consequently produce ion flux 1 , thereby inducing membrane potential changes that lead to signal propagation for neurotransmission 1,2,3,4
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Its also interesting to note that most of the detoxing done by glutathione is occurring in the two most metabolically active organs in human physiologythe liver and the brainas these two organs generate and utilize more glutathione than any other organs
J Biol Chem 2000